Can an overdose of venlafaxine be fatal?

Can an overdose of venlafaxine be fatal?

Venlafaxine overdoses can be life threatening. Signs of toxicity include seizure and prolongation of the QRS and QTc. Large venlafaxine ingestions can cause a severe, reversible cardiomyopathy requiring extracorporeal life support.

What does it feel like to overdose on venlafaxine?

Wyeth’s letter states that the most commonly reported Effexor overdose effects include fast heart rate, changes in consciousness (ranging from sleepiness to coma), seizures, vomiting, and eye pupil dilation.

How much venlafaxine can you take in a day?

Typical maximum dosage: 225 mg per day. If you have more severe depression, your doctor may prescribe a dosage as high as 375 mg per day, taken in three divided doses.

What would happen if I overdose on venlafaxine?

Large overdoses, usually intentional, may produce mental status changes, delirium, seizures, and coma. Overdose greater than 8 grams of venlafaxine may cause slowed cardiac conduction and risk of ventricular dysrhythmia due to sodium and potassium channel block.

How much venlafaxine will cause an overdose?

A typical dose of the SNRI venlafaxine is between 75 and 225 mg per day, taken in two or three divided doses. Lethal outcomes have been seen at doses as low as 2,000 mg (2 g).

Can you take 300 mg of Effexor?

Dosage for major depressive disorder The usual starting dosage of Effexor XR for major depressive disorder (MDD) is 75 mg once daily. The maximum dosage for MDD is 225 mg once daily. However, daily dosages of 300 mg or higher may be needed to treat MDD in some people.

How much venlafaxine can you take?

Is 300 mg of Effexor too much?

How long do they keep you in the hospital after an overdose?

Most Overdose Patients Can Leave ER One Hour After Receiving Naloxone. Most people treated in the emergency room for an opioid overdose can safely leave the hospital in as little as one hour after receiving the opioid overdose antidote naloxone, according to a new study.